Applied Bioinformatics Course [中文]

The Great Men and Women in Bioinformatics

• Margaret Dayhoff - The founder of protein sequence database and the developer of the Point Accepted Mutation (PAM) scoring matrix for sequence alignment.
• Walter Goad - The founder of the nucleotide database GenBank. Walter Goad in front of a terminal accessing the GenBank database.
• Helen Berman - The co-funder of the protein structure database Protein Data Bank (PDB). Her memoir at the American Crystallographic Association.
• Needleman and Christian Wunsch - The developer of the global sequence alignment Needleman-Wunsch Algorithm
• Temple Smith and Michael Waterman - The developer of the local sequence alignment Smith-Waterman Algorithm
• David Lipman - The founder and director of NCBI, and one of the major developers of the sequence similarity database search tool BLAST
• Alex Bateman - The Head of EBI Protein Sequence Resources including UniProt, PFam, RFam, DFam, TreeFam, editor of Bioinformatics and NAR's database issue.
• Chou and Fasman - The developer of the protein secondary structure prediction Chou-Fasman Algorithm
• Henikoff and Henikoff - The developer of the BLOSUM scoring matrix for sequence alignment.
• Chris Sander - The developer of protein secondary structure definition and classification DSSP and one of the founding editors of the journal Bioinformatics
• Amos Bairock - The founder of the protein sequence database Swiss-Prot, and the head of the on-going project neXtProt.

The Senior Chinese Bioinformaticians

• Gu XC - A memorial web site for Prof Gu, the founder of the PKU Center for Bioinformatics.
• Hao BL - Prof Hao started to work on bioinformatics in later 1990'. His book "Bioinformatics Manual" was published in 2000 and updated in 2002. He proposed an alignment-free approach to construct phylogenetic trees using composition vector of bacterial proteome sequences. A paper in Chinese describes some of the features of this approach [PDF]. His Personal Website lists his scientific books and papers as well some interesting articles such as "The Hard Route of the Basic Research of China in the 20th Century" [PDF]
• Zhang CT - Prof Zhang has been working in the computational biology for more than 30 years. He proposed an algorithm, Z-Curve, using a mathematical approach to represent genomic DNA sequences as three-dimensional curves. You may read his paper "A Brief Review: The Z-curve Theory and its Application in Genome Analysis" PMC [PDF]
• Zhao GP - Prof Zhao is a wet-lab biologist. His research projects include genome sequencing and bioinformatics analysis such as the Nature paper of the Leptospira PubMed.

The Collaborative Biologists

• Long MY - Prof Manyuan Long helped us to supervise several PhD students including Zhang Y, Zhu ZL, Chen ZX, Zhang L. He gave several talks for CAAS students on the evolution of new genes [Review] [Jingwei gene 1 ] [Jingwei gene 2]
• Zhu YX - Collaboration on the PPF-1 project
• Zhao JD - Collaboration on the antifungal peptide AFP project, and the cyanobacterial genome assembly project [PubMed]
• Bai SN - Collaboration on several projects including the cucumber flower development [PubMed] and the rice stamen development [PubMed]
• Li ZH - Collaboration on leaf senescence database
• Yang HM - Collaboration on the Fugu cosmid sequence MDR
• Liag SP - Prof Liang was a classmate of mine. We had collaboration on the Spider Toxin project.

The Teaching Assistants

• Rao XC (PhD student of Prof Yi CQ) - Teaching Assistant for PKU22.
• Yang DC (PhD student of Prof Gao G) - Teaching Assistant for PKU20 and PKU21.
• Pan Q (PhD student of Prof Wei WS) - Teaching Assistant for PKU20.
• Xiang W (PhD student of Prof Qu LJ) - Teaching Assistant for PKU19F.
• Wu XK (PhD student of Prof Lu J) - Teaching Assistant for PKU19F.
• Zhuang Y (PhD student of Prof Yi CQ) - Teaching Assistant for PKU18F.
• Huang Y (PhD student of Prof Li Y) - Teaching Assistant for PKU18S.
• Wang Y (PhD student of Prof Jin CW) - Teaching Assistant for PKU17F.
• Ai C (PhD student of Prof Wei LP) - Teaching Assistant for PKU17S.
• Ke L (PhD student of Prof Gao G) - Teaching Assistant for PKU16F.
• Jiang S (PhD student of Prof Gao G) - Teaching Assistant for PKU15s and PKU15F. She gave BLAST lectures for both PKU and CAAS students.
• Wang ZM (M.S. student of Prof Zhao JD) - Teaching Assisitant for PKU14F.
• Kang YJ (PhD student of Prof Gao G) - Teaching Assisitant for PKU14s. She gave BLAST lectures for PKU students.
• Hao DD (PhD student of Prof Guo HW) - Teaching Assistant for PKU13F.
• Guo Y (PhD student of Prof Chai Z) - Teaching Assistant for PKU13S.
• Dou YM (PhD studet of Prof Gao G) - Teaching Assistant for PKU12F.
• Hou M (PhD student of Prof Gao G) - Teaching Assistant for PKU12F
• Wu YT (PhD student of Prof Liu D) - Teaching Assistant for PKU12S.
• Zhu Y (PhD student of Prof Guo HW) - Teaching Assistant for PKU12S.
• Zhao Y - Teaching Assistant for PKU10S1.
• Liu H - Teaching Assistant for PKU10S2.
• Xu LM - Teaching Assistant for PKU09S1.
• Wang J - Teaching Assistant for PKU09S2 and PKU08S2.
• Xie C - Teaching Assistant for PKU09S3.
• Chen ZX - Teaching Assistant for PKU08S1.
• Zhao SQ - Teaching Assistant for CAAS and PKU students.
• Li Z - Teaching Assistant for CAAS and PKU students.
• Kong L - Teaching Assistant for CAAS and PKU students.
• Ye ZQ - Teaching Assistant for CAAS students.