Outline
- Getting started with applied bioinformatics
- An overview of bioinformatics
- The basis of molecular biology
- Bioinformatics resources over the Internet
- International bioinformatics centers (NCBI, EBI, ExPASy, RSCB)
- Literature references (PubMed, NCBI free Bookshelf, bioinformatics
courses, tutorials)
- Databases of molecular biology (sequence, function, structure, genome, secondary databases)
- Bioinformatics tools (programs, packages, online web servers)
- Database query
- Advanced PubMed search and MyNCBI
- UniProt Advanced search
- Database query with the EBI SRS platform
- DNA and protein sequence analysis
- Sequence alignment and dotplot
- Protein sequence analysis
- DNA sequence analysis
- Database similarity search with BLAST
- Phylogenic analysis and tree construction
- Molecular modeling
- Molecular graphics and visualization
- Molecular modeling and structure prediction
- Projects
- Sequence analysis of Pisum sativum post-floral specific gene
- MDR - Gene prediction and dotplot analysis of fugu multi-drug resistance
gene
- Flu - Analysis of influenza A virus nuraminidase
- Seqeunce, structure and function analysis the bar-headed goose
hemoglobin
- CEA - Protein engineering of carcinoembryonic antigen
- Structure comparison of spider toxins and prediction of antifungal
peptide
- Sequence and structure comparison of human metallothioneins
- Systematic analysis of the Arabidopsis transcription factor family
of Squamosa-promoter binding protein
References Books:
-
Jin Xiong, Essential Bioinformatics. 2006, Cambridge University Press.
(order from Amazon),
-
Jean-Michele Claverie and Cedric Notredame, Bioinformatics for Dummies.
2007, 2nd edition, Wiely
(order from Amazon),
-
David Mount, Bioinformatics: Sequence and Genome Analysis. Cold Spring
Laboratory Press, 2001, 2nd Edition
(order from Amazon,
online reading)
24 December 2023,
J Luo,
CBI,
PKU, Beijing, China