BLAST Search results
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Blast search for open reading frame 1 (3397-4062)
GeneQuiz Result at EBI server
BLASTP 2.0.6 [Sept-16-1998]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 3397 3397..4062
(222 letters)
Database: swissprot36
74,019 sequences; 26,840,295 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 153 2e-37
sp|P21439|MDR3_HUMAN MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT... 153 3e-37
sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT... 150 2e-36
sp|P21440|MDR2_MOUSE MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROT... 149 5e-36
sp|P06795|MDR1_MOUSE MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 148 1e-35
sp|P21447|MDR3_MOUSE MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT... 147 1e-35
sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 147 2e-35
sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEI... 145 5e-35
sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROT... 145 9e-35
sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEI... 142 6e-34
sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESISTANCE PROTEIN PMD1. 78 2e-14
sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 75 2e-13
sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT... 74 3e-13
sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 50 (P-... 71 1e-12
sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT... 65 1e-10
sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-... 57 3e-08
sp|Q03519|TAP2_HUMAN ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (PEPTI... 45 1e-04
sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (HISTO... 39 0.005
sp|P12866|STE6_YEAST MATING FACTOR A SECRETION PROTEIN STE6 (MUL... 38 0.016
sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANSPORTER 2 (APT2). 38 0.016
sp|P53706|HST6_CANAL ATP-DEPENDENT PERMEASE HST6 (STE6 HOMOLOG). 37 0.036
sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA. 36 0.062
sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA. 36 0.062
sp|P21958|TAP1_MOUSE ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (HISTO... 32 0.92
sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1). 31 2.7
sp|Q10616|Y029_MYCTU HYPOTHETICAL 56.0 KD PROTEIN CY373.09C. 31 2.7
sp|P12449|ENV_HV2SB ENVELOPE POLYPROTEIN GP160 PRECURSOR (CONTAI... 30 3.6
sp|Q23868|TAGC_DICDI PRESTALK-SPECIFIC PROTEIN TAGC PRECURSOR (E... 30 4.7
sp|P54683|TAGB_DICDI PRESTALK-SPECIFIC PROTEIN TAGB PRECURSOR (E... 29 6.1
sp|P24105|ENV_HV2CA ENVELOPE POLYPROTEIN GP160 PRECURSOR (CONTAI... 29 8.0
sp|P13568|MDR_PLAFF MULTIDRUG RESISTANCE PROTEIN (CHLOROQUINE RE... 29 8.0
>sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
Length = 1280
Score = 153 bits (383), Expect = 2e-37
Identities = 78/161 (48%), Positives = 101/161 (62%), Gaps = 29/161 (18%)
Query: 17 YSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWY 76
+ NL+ R++ YYS +G VLV AY+Q+S W L A RQ +IR+ FFH IM+Q+I W+
Sbjct: 104 FMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWF 163
Query: 77 DVTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLI 136
DV + GELNTRLT+ DV KI EGIGDK G+
Sbjct: 164 DVHDVGELNTRLTD-----------------------------DVSKINEGIGDKIGMFF 194
Query: 137 QAASTFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
Q+ +TF T F++GF GWKLTLVILAISPVLGLSAA+++K+
Sbjct: 195 QSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKI 235
Score = 67.5 bits (162), Expect = 2e-11
Identities = 39/153 (25%), Positives = 72/153 (46%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTE--TGEL 84
FS+ + LG + +LQ + KR+R + F +++QD+SW+D + TG L
Sbjct: 755 FSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGAL 814
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
TRL A+D +++ IG + ++ Q + T
Sbjct: 815 TTRL-----------------------------ANDAAQVKGAIGSRLAVITQNIANLGT 845
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I F++GW+LTL++LAI P++ ++ + K+
Sbjct: 846 GIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKM 878
>sp|P21439|MDR3_HUMAN MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3).
Length = 1279
Score = 153 bits (382), Expect = 3e-37
Identities = 73/152 (48%), Positives = 99/152 (65%), Gaps = 29/152 (19%)
Query: 26 RFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELN 85
R++ YYS LG VLV AY+Q+S WTL A RQ ++IR+ FFH I++Q+I W+D+ +T ELN
Sbjct: 115 RYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELN 174
Query: 86 TRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITS 145
TRLT+ D+ KI EGIGDK G+ QA +TF
Sbjct: 175 TRLTD-----------------------------DISKISEGIGDKVGMFFQAVATFFAG 205
Query: 146 FVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
F++GF+ GWKLTLVI+AISP+LGLSAA+++K+
Sbjct: 206 FIVGFIRGWKLTLVIMAISPILGLSAAVWAKI 237
Score = 64.4 bits (154), Expect = 2e-10
Identities = 39/153 (25%), Positives = 69/153 (44%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+ + LG +LQ + +R+R + F +++QD+SW+D TG L
Sbjct: 754 FSLIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGAL 813
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
+TRL A D ++Q G + L+ Q + T
Sbjct: 814 STRL-----------------------------ATDAAQVQGATGTRLALIAQNIANLGT 844
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I F++GW+LTL++LA+ P++ +S + K+
Sbjct: 845 GIIISFIYGWQLTLLLLAVVPIIAVSGIVEMKL 877
>sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3).
Length = 1281
Score = 150 bits (375), Expect = 2e-36
Identities = 73/152 (48%), Positives = 98/152 (64%), Gaps = 29/152 (19%)
Query: 26 RFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELN 85
R++ YYS LG VLV AY+Q+S WTL A RQ K+IR+ FFH I++Q++ W+D+ T ELN
Sbjct: 115 RYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQNFFHAILRQEMGWFDIKGTTELN 174
Query: 86 TRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITS 145
TRLT+ D+ KI EGIGDK G+ QA +TF
Sbjct: 175 TRLTD-----------------------------DISKISEGIGDKVGMFFQAVATFFAG 205
Query: 146 FVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
F++GF+ GWKLTLVI+AISP+LGLSAA+++K+
Sbjct: 206 FIVGFIRGWKLTLVIMAISPILGLSAAVWAKI 237
Score = 57.8 bits (137), Expect = 2e-08
Identities = 38/153 (24%), Positives = 67/153 (42%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+ + LG +LQ + R+R + F +++QD+SW+D TG L
Sbjct: 756 FSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDYKNSTGAL 815
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
+TRL A D ++Q G + L+ Q + T
Sbjct: 816 STRL-----------------------------ATDRAQVQGATGTRLALIAQNTANLGT 846
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I F++GW+LTL++L++ P + +S + K+
Sbjct: 847 GIIISFIYGWQLTLLLLSVVPFIAVSGIVEMKM 879
>sp|P21440|MDR2_MOUSE MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2).
Length = 1276
Score = 149 bits (372), Expect = 5e-36
Identities = 73/152 (48%), Positives = 97/152 (63%), Gaps = 29/152 (19%)
Query: 26 RFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELN 85
R++ YYS LG VLV AY+Q+S WTL A RQ K+IR+ FFH I++Q++ W+D+ T ELN
Sbjct: 112 RYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMGWFDIKGTTELN 171
Query: 86 TRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITS 145
TRLT+ DV KI EGIGDK G+ QA +TF
Sbjct: 172 TRLTD-----------------------------DVSKISEGIGDKVGMFFQAIATFFAG 202
Query: 146 FVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
F++GF+ GWKLTLVI+AISP+LGLS A+++K+
Sbjct: 203 FIVGFIRGWKLTLVIMAISPILGLSTAVWAKI 234
Score = 58.9 bits (140), Expect = 7e-09
Identities = 38/153 (24%), Positives = 67/153 (42%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+ + LG +LQ + R+R + F +++QD+SW+D TG L
Sbjct: 751 FSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGAL 810
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
+TRL A D ++Q G K L+ Q + T
Sbjct: 811 STRL-----------------------------ATDAAQVQGATGTKLALIAQNTANLGT 841
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I F++GW+LTL++L++ P + ++ + K+
Sbjct: 842 GIIISFIYGWQLTLLLLSVVPFIAVAGIVEMKM 874
>sp|P06795|MDR1_MOUSE MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
Length = 1276
Score = 148 bits (369), Expect = 1e-35
Identities = 74/160 (46%), Positives = 102/160 (63%), Gaps = 29/160 (18%)
Query: 18 SNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD 77
S+L+ ++ YY+ +G VL+VAY+Q+SLW L A RQ +IR+ FFH IM Q+I W+D
Sbjct: 104 SSLEEEMAIYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFD 163
Query: 78 VTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQ 137
V + GELNTRLT+ DV KI +GIGDK G+ Q
Sbjct: 164 VHDVGELNTRLTD-----------------------------DVSKINDGIGDKIGMFFQ 194
Query: 138 AASTFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+ +TF+ F+IGF+ GWKLTLVILA+SP++GLS+AL++KV
Sbjct: 195 SITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKV 234
Score = 59.3 bits (141), Expect = 6e-09
Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+++ ++G V + Q + KR+R + F +++QDISW+D TG L
Sbjct: 753 FSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSL 812
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
TRL A D ++ +G + ++ Q + T
Sbjct: 813 TTRL-----------------------------ASDASSVKGAMGARLAVVTQNVANLGT 843
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
++ V+GW+LTL+++ I P++ L + K+
Sbjct: 844 GVILSLVYGWQLTLLLVVIIPLIVLGGIIEMKL 876
>sp|P21447|MDR3_MOUSE MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3) (MDR1A).
Length = 1276
Score = 147 bits (368), Expect = 1e-35
Identities = 75/161 (46%), Positives = 98/161 (60%), Gaps = 29/161 (18%)
Query: 17 YSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWY 76
++ L+ ++ YY+ +G VL+VAY+Q+S W L A RQ +IR+ FFH IM Q+I W+
Sbjct: 100 FAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWF 159
Query: 77 DVTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLI 136
DV + GELNTRLT+ DV KI EGIGDK G+
Sbjct: 160 DVHDVGELNTRLTD-----------------------------DVSKINEGIGDKIGMFF 190
Query: 137 QAASTFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
QA +TF F+IGF GWKLTLVILAISPVLGLSA +++K+
Sbjct: 191 QAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKI 231
Score = 65.2 bits (156), Expect = 1e-10
Identities = 38/153 (24%), Positives = 71/153 (45%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTE--TGEL 84
FS+ + ILG + +LQ + KR+R + F +++QD+SW+D + TG L
Sbjct: 751 FSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGAL 810
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
TRL A+D +++ G + ++ Q + T
Sbjct: 811 TTRL-----------------------------ANDAAQVKGATGSRLAVIFQNIANLGT 841
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I ++GW+LTL++LAI P++ ++ + K+
Sbjct: 842 GIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKM 874
>sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
Length = 1276
Score = 147 bits (367), Expect = 2e-35
Identities = 75/161 (46%), Positives = 97/161 (59%), Gaps = 29/161 (18%)
Query: 17 YSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWY 76
+ L+ ++ YY+ +G VL+VAY+Q+S W L A RQ +IR+ FFH IM Q+I W+
Sbjct: 101 FGKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWF 160
Query: 77 DVTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLI 136
DV + GELNTRLT+ DV KI EGIGDK G+
Sbjct: 161 DVHDVGELNTRLTD-----------------------------DVSKINEGIGDKIGMFF 191
Query: 137 QAASTFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
QA +TF F+IGF GWKLTLVILAISPVLGLSA +++K+
Sbjct: 192 QAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKI 232
Score = 63.2 bits (151), Expect = 4e-10
Identities = 38/153 (24%), Positives = 70/153 (44%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+ + ILG + +LQ + KR+R + F +++QD+SW+D TG L
Sbjct: 752 FSLLFLILGVISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGAL 811
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
TRL A+D +++ G + ++ Q + T
Sbjct: 812 TTRL-----------------------------ANDAGQVKGATGARLAVITQNIANLGT 842
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I ++GW+LTL++LAI P++ ++ + K+
Sbjct: 843 GIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKM 875
>sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
Length = 1277
Score = 145 bits (363), Expect = 5e-35
Identities = 71/151 (47%), Positives = 97/151 (64%), Gaps = 29/151 (19%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNT 86
++ YY+ +G VL+VAY+Q+SLW L A RQ +IR+ FFH IM Q+I W+DV + GELNT
Sbjct: 113 YAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVNDAGELNT 172
Query: 87 RLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSF 146
RLT+ DV KI +GIGDK G+ Q+ +TF F
Sbjct: 173 RLTD-----------------------------DVSKINDGIGDKLGMFFQSITTFSAGF 203
Query: 147 VIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+IGF+ GWKLTLVILA+SP++GLS+A+++KV
Sbjct: 204 IIGFISGWKLTLVILAVSPLIGLSSAMWAKV 234
Score = 53.1 bits (125), Expect = 4e-07
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 33/155 (21%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+ + ++G V + Q + KR+R + F +++QDISW+D TG L
Sbjct: 753 FSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSL 812
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
TRL A D ++ +G + ++ Q + T
Sbjct: 813 TTRL-----------------------------ASDASNVKGAMGSRLAVVTQNVANLGT 843
Query: 145 SFVIG--FVHGWKLTLVILAISPVLGLSAALYSKV 177
++ V+GW+LTL+++ I P++ L + K+
Sbjct: 844 GIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKL 878
>sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2).
Length = 1276
Score = 145 bits (361), Expect = 9e-35
Identities = 69/151 (45%), Positives = 98/151 (64%), Gaps = 29/151 (19%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNT 86
++ YY+ +G VL+VAY+Q+S W L A RQ +IR+ FFH IM Q+I W+DV + GELNT
Sbjct: 113 YAYYYTGIGAGVLIVAYIQVSFWCLAAGRQINKIRQKFFHAIMNQEIGWFDVHDIGELNT 172
Query: 87 RLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSF 146
RLT+ DV KI +GIGDK G+ Q+ +TF+ +F
Sbjct: 173 RLTD-----------------------------DVSKINDGIGDKIGMFFQSIATFLAAF 203
Query: 147 VIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
++GF+ GWKLTLVILA+SP++GLS+A+++KV
Sbjct: 204 IVGFISGWKLTLVILAVSPLIGLSSAMWAKV 234
Score = 60.1 bits (143), Expect = 3e-09
Identities = 38/153 (24%), Positives = 67/153 (42%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+++ ++G V + Q + KR+R + F +++QDISW+D TG L
Sbjct: 753 FSLFFLVMGMICFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHRNSTGAL 812
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
TRL A D ++ + + + Q + T
Sbjct: 813 TTRL-----------------------------ASDAANVKGAMSSRLAGITQNVANLGT 843
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I V+GW+LTL+++ I+P++ LS + KV
Sbjct: 844 GIIISLVYGWQLTLLLVVIAPLIILSGMMEMKV 876
>sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2).
Length = 1278
Score = 142 bits (354), Expect = 6e-34
Identities = 68/152 (44%), Positives = 96/152 (62%), Gaps = 29/152 (19%)
Query: 26 RFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELN 85
R++ YYS LG VL+ AY+Q+S WTL A RQ ++IR+ FFH I++Q++ W+D+ T ELN
Sbjct: 112 RYAYYYSGLGGGVLLAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEMGWFDIKGTTELN 171
Query: 86 TRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITS 145
TRLT+ D+ KI EGIGDK G+ QA +TF
Sbjct: 172 TRLTD-----------------------------DISKISEGIGDKVGMFFQAIATFFAG 202
Query: 146 FVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
F++GF+ GWKLTLVI+AI+ +LGLS A+++K+
Sbjct: 203 FIVGFIRGWKLTLVIMAITAILGLSTAVWAKI 234
Score = 57.4 bits (136), Expect = 2e-08
Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 31/153 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD--VTETGEL 84
FS+ + LG +LQ + R+R + F +++QD+SW+D TG L
Sbjct: 753 FSLVFLGLGVHSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGAL 812
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
+TRL A D ++Q G + L+ Q + T
Sbjct: 813 STRL-----------------------------ATDAAQVQGATGTRLALIAQNTANLGT 843
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+I F++GW+LTL++L++ P + ++ + K+
Sbjct: 844 GIIISFIYGWQLTLLLLSVVPFIAVAGIVEMKM 876
>sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESISTANCE PROTEIN PMD1.
Length = 1362
Score = 77.6 bits (188), Expect = 2e-14
Identities = 42/152 (27%), Positives = 72/152 (46%), Gaps = 29/152 (19%)
Query: 16 GYSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISW 75
G S+ Q F +Y+ + V +Y+ + + R A+RIR+ + H I+ Q+I +
Sbjct: 131 GASSFQHTVDHFCLYFIYIAIGVFGCSYIYTVTFIIAGERIARRIRQDYLHAILSQNIGY 190
Query: 76 YDVTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLL 135
+D GE+ TR+T D IQ+G+G+K GL+
Sbjct: 191 FDRLGAGEITTRITT-----------------------------DTNFIQDGLGEKVGLV 221
Query: 136 IQAASTFITSFVIGFVHGWKLTLVILAISPVL 167
A +TF++ FVI F+ WK TL++ ++ P +
Sbjct: 222 FFAIATFVSGFVIAFIRHWKFTLILSSMFPAI 253
Score = 40.2 bits (92), Expect = 0.003
Identities = 40/153 (26%), Positives = 68/153 (44%), Gaps = 38/153 (24%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQA--KRIRELFFHGIMQQDISWYDVTET--G 82
F++Y+ IL V AY +S + +T A +A +RIR F +++QD+ ++D +E G
Sbjct: 838 FAVYWLILAI-VQFFAYA-ISNFAMTYAMEAVLQRIRYHLFRTLLRQDVEFFDRSENTVG 895
Query: 83 ELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGI-GDKAGLLIQAAST 141
+ T L+ + + EG+ G G Q +
Sbjct: 896 AITTSLSTKIQSL------------------------------EGLSGPTLGTFFQILTN 925
Query: 142 FITSFVIGFVHGWKLTLVILAISPVLGLSAALY 174
I+ ++ GWKL LV L+ SPV+ ++A Y
Sbjct: 926 IISVTILSLATGWKLGLVTLSTSPVI-ITAGYY 957
>sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN A).
Length = 1321
Score = 74.5 bits (180), Expect = 2e-13
Identities = 39/146 (26%), Positives = 69/146 (46%), Gaps = 29/146 (19%)
Query: 31 YSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTE 90
Y+ + + + ++ + A + R+R F I++Q+ISW+D +G L T+L +
Sbjct: 142 YAAMTVGMWAAGQIIVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFD 201
Query: 91 WVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSFVIGF 150
++ +++EG GDK G+ Q S FIT F++ F
Sbjct: 202 -----------------------------NLERVKEGTGDKIGMAFQYLSQFITGFIVAF 232
Query: 151 VHGWKLTLVILAISPVLGLSAALYSK 176
H W+LTLV+LA++P+ L +K
Sbjct: 233 THSWQLTLVMLAVTPIQALCGFAIAK 258
Score = 37.5 bits (85), Expect = 0.021
Identities = 26/149 (17%), Positives = 61/149 (40%), Gaps = 31/149 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTE--TGEL 84
+++ + +L A + ++L + + + +R F ++ Q I ++D + +G++
Sbjct: 796 WALMFLVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGKI 855
Query: 85 NTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFIT 144
+TRL A DV ++ I + +I + +
Sbjct: 856 STRL-----------------------------ATDVPNLRTAIDFRFSTVITTLVSMVA 886
Query: 145 SFVIGFVHGWKLTLVILAISPVLGLSAAL 173
+ F +GW++ L+I+AI P++ L
Sbjct: 887 GIGLAFFYGWQMALLIIAILPIVAFGQYL 915
>sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
Length = 1280
Score = 73.7 bits (178), Expect = 3e-13
Identities = 43/150 (28%), Positives = 66/150 (43%), Gaps = 29/150 (19%)
Query: 28 SIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTR 87
S+ +G A+L+ + WT+ A RQ RIR LFF +++QDI W+D G L R
Sbjct: 115 SLIMVYVGIAMLIACAGHVMCWTVAACRQVARIRLLFFRAVLRQDIGWHDEHSPGALTAR 174
Query: 88 LTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSFV 147
+T D IQ GI DK I S + ++
Sbjct: 175 MT-----------------------------GDTRVIQNGINDKLSQGIMNGSMGVIGYI 205
Query: 148 IGFVHGWKLTLVILAISPVLGLSAALYSKV 177
GFV W+LTL+++ + P + + AA+ +
Sbjct: 206 AGFVFSWELTLMMIGMMPFIIVMAAIIGSI 235
Score = 41.4 bits (95), Expect = 0.001
Identities = 31/111 (27%), Positives = 49/111 (43%), Gaps = 31/111 (27%)
Query: 59 RIRELFFHGIMQQDISWYDVT--ETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFP 116
+IR L F IM+QDI+++D+ + G L AG++ C
Sbjct: 791 KIRVLLFRQIMRQDINFFDIPGRDAGTL-------------------AGMLSGDC----E 827
Query: 117 GAHDVYKIQEGIGDKAGLLIQAASTFITSFVIGFVHGWKLTLVILAISPVL 167
H ++ G GL +Q + V+GF++ WKL LV LA P++
Sbjct: 828 AVHQLW------GPSIGLKVQTMCIIASGLVVGFIYQWKLALVALACMPLM 872
>sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 50 (P-GLYCOPROTEIN 50).
Length = 1302
Score = 71.4 bits (172), Expect = 1e-12
Identities = 42/155 (27%), Positives = 75/155 (48%), Gaps = 29/155 (18%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNT 86
F I + A+ ++ L + L A Q RIR+LF +++QDI+WYD + +
Sbjct: 118 FGIGSLVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFAS 177
Query: 87 RLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSF 146
++TE D+ K++EGIG+K +++ TF+
Sbjct: 178 KMTE-----------------------------DLDKLKEGIGEKIVIVVFLIMTFVIGI 208
Query: 147 VIGFVHGWKLTLVILAISPVLGLSAALYSKVNISI 181
V FV+GWKLTLV+L+ P + + ++ +++ S+
Sbjct: 209 VSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSL 243
Score = 50.4 bits (118), Expect = 3e-06
Identities = 37/150 (24%), Positives = 63/150 (41%), Gaps = 31/150 (20%)
Query: 26 RFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDV--TETGE 83
+ S+ + +G + LQ ++T + R+R+ F I+ QDI+++D G
Sbjct: 777 KISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGA 836
Query: 84 LNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFI 143
L +RL A D +Q G + G ++QA +T +
Sbjct: 837 LCSRL-----------------------------ASDCSNVQGATGARVGTMLQAVATLV 867
Query: 144 TSFVIGFVHGWKLTLVILAISPVLGLSAAL 173
V+GFV W+ TL+ L P++ LS L
Sbjct: 868 VGMVVGFVFSWQQTLLTLVTLPLVCLSVYL 897
>sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN C).
Length = 1254
Score = 64.8 bits (155), Expect = 1e-10
Identities = 38/140 (27%), Positives = 63/140 (44%), Gaps = 29/140 (20%)
Query: 27 FSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNT 86
F + Y LG A+ + +Y S R+ IR+ + +++QD W+D T G L
Sbjct: 98 FCLRYFYLGVALFLCSYFANSCLYTLCERRLHCIRKKYLKSVLRQDAKWFDETTIGGLTQ 157
Query: 87 RLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSF 146
+++ + KI++GIGDK G+L+ +TFI+
Sbjct: 158 KMSSGIE-----------------------------KIKDGIGDKVGVLVGGVATFISGV 188
Query: 147 VIGFVHGWKLTLVILAISPV 166
IGF W+LTLV++ P+
Sbjct: 189 SIGFYMCWQLTLVMMITVPL 208
Score = 34.8 bits (78), Expect = 0.14
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 28 SIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVT--ETGELN 85
S+++ +L F + + SL + R+R F IMQQD S++D + G L
Sbjct: 737 SLWFILLAFTGGISTLISGSLLGKAGETMSGRLRMDVFRNIMQQDASYFDDSRHNVGSLT 796
Query: 86 TRLTEWVTH----IIHTPVPVTAGVVVIICGV 113
+RL + I V G+V + CGV
Sbjct: 797 SRLATDAPNVQAAIDQRLAEVLTGIVSLFCGV 828
>sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-GLYCOPROTEIN 65).
Length = 1302
Score = 57.0 bits (135), Expect = 3e-08
Identities = 37/144 (25%), Positives = 61/144 (41%), Gaps = 33/144 (22%)
Query: 28 SIYYSILGFAVLVVAYLQ----MSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGE 83
SI Y IL VV ++ + ++ + A RQ R+R F +++QDI W+D+
Sbjct: 117 SISYGILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIRQDIGWHDLASKQN 176
Query: 84 LNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFI 143
+ + DV KI++GI +K G + FI
Sbjct: 177 FTQSMVD-----------------------------DVEKIRDGISEKVGHFVYLVVGFI 207
Query: 144 TSFVIGFVHGWKLTLVILAISPVL 167
+ I F +GWKLTL + + P++
Sbjct: 208 ITVAISFSYGWKLTLAVSSYIPLV 231
Score = 49.2 bits (115), Expect = 6e-06
Identities = 39/151 (25%), Positives = 64/151 (41%), Gaps = 33/151 (21%)
Query: 31 YSILGFAVL--VVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDV--TETGELNT 86
++ LG A L +V +LQ L+ R+R + F+ ++ Q++ W+D G L+
Sbjct: 777 WACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSA 836
Query: 87 RLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSF 146
RL+ + IQ IG +IQA S FI+S
Sbjct: 837 RLSG-----------------------------EAVDIQGAIGYPLSGMIQALSNFISSV 867
Query: 147 VIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+ + WKL L+ LA P++ S L +K+
Sbjct: 868 SVAMYYNWKLALLCLANCPIIVGSVILEAKM 898
>sp|Q03519|TAP2_HUMAN ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (PEPTIDE TRANSPORTER TAP2)
(PEPTIDE TRANSPORTER PSF2) (PEPTIDE SUPPLY FACTOR 2)
(PSF-2) (PEPTIDE TRANSPORTER INVOLVED IN ANTIGEN
PROCESSING 2).
Length = 686
Score = 44.9 bits (104), Expect = 1e-04
Identities = 28/91 (30%), Positives = 51/91 (55%), Gaps = 2/91 (2%)
Query: 19 NLQPLFFRFSIYYSIL-GFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYD 77
+ P F +I++ L F + A + +T T +R RIRE F +++QD+ ++
Sbjct: 183 DFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRINLRIREQLFSSLLRQDLGFFQ 242
Query: 78 VTETGELNTRLTEWVTHIIHTPVPVTAGVVV 108
T+TGELN+RL+ T ++ +P+ A V++
Sbjct: 243 ETKTGELNSRLSSDTT-LMSNWLPLNANVLL 272
>sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (HISTOCOMPATIBILITY ANTIGEN
MODIFIER 2).
Length = 702
Score = 39.5 bits (90), Expect = 0.005
Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 52 TAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTEWVTHIIHTPVPVTAGVVV 108
T +R RIRE F +++QD+ ++ T+TGELN+RL+ T ++ +P A +++
Sbjct: 216 TMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSS-DTSLMSRWLPFNANILL 271
>sp|P12866|STE6_YEAST MATING FACTOR A SECRETION PROTEIN STE6 (MULTIPLE DRUG RESISTANCE
PROTEIN HOMOLOG) (P-GLYCOPROTEIN).
Length = 1290
Score = 37.9 bits (86), Expect = 0.016
Identities = 34/168 (20%), Positives = 62/168 (36%), Gaps = 29/168 (17%)
Query: 11 YLAEFGYSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQ 70
++A + L + S+ LG A + V +L ++ W RQ RIR ++
Sbjct: 58 FVANGSHQGLYSQLVQRSMAVMALGAASVPVMWLSLTSWMHIGERQGFRIRSQILEAYLE 117
Query: 71 QD-ISWYDVTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIG 129
+ + WYD E +L T I V +++
Sbjct: 118 EKPMEWYDNNE------KLLGDFTQINRC----------------------VEELRSSSA 149
Query: 130 DKAGLLIQAASTFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
+ + + Q F + W LTL+IL SP++ A ++S++
Sbjct: 150 EASAITFQNLVAICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRM 197
Score = 32.5 bits (72), Expect = 0.71
Identities = 15/46 (32%), Positives = 29/46 (62%), Gaps = 4/46 (8%)
Query: 136 IQAASTFITSFVIGF----VHGWKLTLVILAISPVLGLSAALYSKV 177
+ A ++F+T IG V GWKL+LV +++ P++ + +A+Y +
Sbjct: 840 LSAMTSFVTVSTIGLIWALVSGWKLSLVCISMFPLIIIFSAIYGGI 885
>sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANSPORTER 2 (APT2).
Length = 703
Score = 37.9 bits (86), Expect = 0.016
Identities = 15/31 (48%), Positives = 25/31 (80%)
Query: 59 RIRELFFHGIMQQDISWYDVTETGELNTRLT 89
RIRE F +++QD++++ T+TGELN+RL+
Sbjct: 224 RIREQLFSSLLRQDLAFFQETKTGELNSRLS 254
>sp|P53706|HST6_CANAL ATP-DEPENDENT PERMEASE HST6 (STE6 HOMOLOG).
Length = 1323
Score = 36.7 bits (83), Expect = 0.036
Identities = 29/150 (19%), Positives = 57/150 (37%), Gaps = 28/150 (18%)
Query: 34 LGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTEWVT 93
+G +++ +L M W Q R R ++ I+ + SWYD + L +LT+
Sbjct: 100 IGCCKMILVWLGMFTWLKFGEIQQSRARMQIYNKIINESQSWYDSKQN--LIGQLTQ--- 154
Query: 94 HIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSFVIGFVHG 153
+ C + +++ G+ L+Q + ++ F
Sbjct: 155 --------------INRC---------IEELRSCNGEILASLMQTIVLILALLIMSFYQS 191
Query: 154 WKLTLVILAISPVLGLSAALYSKVNISIHQ 183
W TL+I+A P++ L + K+ Q
Sbjct: 192 WSTTLIIMASFPIMALCGWYFGKLTYKAQQ 221
Score = 33.2 bits (74), Expect = 0.41
Identities = 30/142 (21%), Positives = 53/142 (37%), Gaps = 25/142 (17%)
Query: 40 VVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTEWVTHIIHTP 99
V +YL + +R+L F + QD+S++ +T ++ +T + +
Sbjct: 735 VTSYLSEFILNYCGENWIVSLRQLTFFKLNNQDLSFFTGFDTNWSSSEITALLMN----- 789
Query: 100 VPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAASTFITSFVIGFVHGWKLTLV 159
D ++ I LL S + + V GWKL LV
Sbjct: 790 --------------------DTRDLRNLISQFFPLLANLVSMTLIGIIWSIVSGWKLALV 829
Query: 160 ILAISPVLGLSAALYSKVNISI 181
++ P++ L LY K+ SI
Sbjct: 830 GISFVPLVLLVTVLYGKILESI 851
>sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA.
Length = 587
Score = 36.0 bits (81), Expect = 0.062
Identities = 26/117 (22%), Positives = 46/117 (39%), Gaps = 30/117 (25%)
Query: 61 RELFFHGIMQQDISWYDVTETGELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHD 120
R LF H +M +S++D TG L +R+T +D
Sbjct: 106 RRLFKH-LMFMPVSFFDQNSTGRLLSRIT-----------------------------YD 135
Query: 121 VYKIQEGIGDKAGLLIQAASTFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKV 177
I +++ + I+ F + F W+LT+V+ I P++ + L SK+
Sbjct: 136 SQMIASSSSGSLITIVREGAYIISLFAVMFYTSWELTIVLFIIGPIIAVLIRLVSKI 192
>sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA.
Length = 582
Score = 36.0 bits (81), Expect = 0.062
Identities = 25/149 (16%), Positives = 63/149 (41%), Gaps = 37/149 (24%)
Query: 33 ILGFAVL--VVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTE 90
++G +L + +Y+ + + + +R F +M +S++D TG L +R+T
Sbjct: 71 VIGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRIT- 129
Query: 91 WVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLI---QAASTFITSFV 147
Y ++ +G LI + ++ I F+
Sbjct: 130 -------------------------------YDSEQVASSSSGALITVVREGASIIGLFI 158
Query: 148 IGFVHGWKLTLVILAISPVLGLSAALYSK 176
+ F + W+L+++++ ++P++ ++ + SK
Sbjct: 159 MMFYYSWQLSIILIVLAPIVSIAIRVVSK 187
>sp|P21958|TAP1_MOUSE ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (HISTOCOMPATIBILITY ANTIGEN
MODIFIER 1).
Length = 724
Score = 32.1 bits (71), Expect = 0.92
Identities = 34/160 (21%), Positives = 55/160 (34%), Gaps = 29/160 (18%)
Query: 22 PLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTET 81
P F R SIL A + + ++ +T R+ F +++Q+ ++
Sbjct: 198 PSFTRNIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREVFRAVLRQETGFFLKNPA 257
Query: 82 GELNTRLTEWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEGIGDKAGLLIQAAST 141
G + +R+TE D + E I D LL+
Sbjct: 258 GSITSRVTE-----------------------------DTANVCESISDTLSLLLWYLGR 288
Query: 142 FITSFVIGFVHGWKLTLVILAISPVLGLSAALYSKVNISI 181
+ V F LTLV L P+L L KV+ S+
Sbjct: 289 ALCLLVFMFWGSPYLTLVTLINLPLLFLLPKKLGKVHQSL 328
>sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1).
Length = 725
Score = 30.5 bits (67), Expect = 2.7
Identities = 16/74 (21%), Positives = 33/74 (43%)
Query: 22 PLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTET 81
P F R IL A V+ + ++ +T R+ F ++ Q+ ++ T
Sbjct: 199 PSFARNMWLMCILTIASTVLEFAGDGIYNITMGHMHSRVHGEVFRAVLHQETGFFLKNPT 258
Query: 82 GELNTRLTEWVTHI 95
G + +R+TE +++
Sbjct: 259 GSITSRVTEDTSNV 272
>sp|Q10616|Y029_MYCTU HYPOTHETICAL 56.0 KD PROTEIN CY373.09C.
Length = 521
Score = 30.5 bits (67), Expect = 2.7
Identities = 29/97 (29%), Positives = 43/97 (43%), Gaps = 12/97 (12%)
Query: 76 YDVTETGELNTRLT--------EWVTHIIHTPVPVTAGVVVIICGVRFPGAHDVYKIQEG 127
Y VT T LN R WV + + +G V+ + V+ D Q
Sbjct: 48 YSVTATSMLNRRKAILDYLQGAVWVLPTFGVAIGLGSGAVLSMIPVKSGTLIDKLMFQGT 107
Query: 128 IGDKAGLLIQAASTFITSFVIGFVHGWKLTLVILAIS 164
GD G+LI ++T IT+ IG V + LT++ L I+
Sbjct: 108 PGDARGVLIVVSATMITT--IGIV--FSLTVLSLQIA 140
>sp|P12449|ENV_HV2SB ENVELOPE POLYPROTEIN GP160 PRECURSOR (CONTAINS: GP120 AND GP41).
Length = 846
Score = 30.1 bits (66), Expect = 3.6
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 13 AEFGYSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQD 72
AE YS+ R + LGF L A M +LT + Q++ + F GI+QQ
Sbjct: 490 AEKRYSSAPGRHKRGVLVLGFLGF--LTTAGAAMGAASLTLSAQSRTL----FRGIVQQQ 543
Query: 73 ISWYDVTETGELNTRLTEWVT 93
DV + + RLT W T
Sbjct: 544 QQLLDVVKRQQEMLRLTVWGT 564
>sp|Q23868|TAGC_DICDI PRESTALK-SPECIFIC PROTEIN TAGC PRECURSOR (EC 3.4.21.-).
Length = 1743
Score = 29.7 bits (65), Expect = 4.7
Identities = 17/47 (36%), Positives = 24/47 (50%), Gaps = 3/47 (6%)
Query: 133 GLLIQAAS---TFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSK 176
G+L+ A+ F+ S V F WKL+LV A PVL + S+
Sbjct: 1145 GILLSIATGLCKFVGSLVFIFTISWKLSLVFFATVPVLAFITQIQSQ 1191
>sp|P54683|TAGB_DICDI PRESTALK-SPECIFIC PROTEIN TAGB PRECURSOR (EC 3.4.21.-).
Length = 1905
Score = 29.3 bits (64), Expect = 6.1
Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 133 GLLIQAAS---TFITSFVIGFVHGWKLTLVILAISPVLGLSAALYSK 176
G+L+ A+ + S V F WKL+L A P+LGL + S+
Sbjct: 1194 GILLSIATGVCKLVGSLVFIFTISWKLSLAFFAAVPILGLVTQIQSQ 1240
>sp|P24105|ENV_HV2CA ENVELOPE POLYPROTEIN GP160 PRECURSOR (CONTAINS: GP120 AND GP41).
Length = 859
Score = 29.0 bits (63), Expect = 8.0
Identities = 22/69 (31%), Positives = 33/69 (46%), Gaps = 5/69 (7%)
Query: 33 ILGF-AVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDISWYDVTETGELNTRLTEW 91
+LGF L A + M +LT + Q++ + GI+QQ DV + + RLT W
Sbjct: 516 VLGFLGFLTTAGVAMGTASLTLSAQSRTL----LAGIVQQQQQLLDVVKRQQELLRLTVW 571
Query: 92 VTHIIHTPV 100
T I+ V
Sbjct: 572 GTKILQARV 580
>sp|P13568|MDR_PLAFF MULTIDRUG RESISTANCE PROTEIN (CHLOROQUINE RESISTANCE PROTEIN).
Length = 1419
Score = 29.0 bits (63), Expect = 8.0
Identities = 14/63 (22%), Positives = 32/63 (50%)
Query: 15 FGYSNLQPLFFRFSIYYSILGFAVLVVAYLQMSLWTLTAARQAKRIRELFFHGIMQQDIS 74
F ++NL+ ++SIY ++ A+ + L+ + K ++ F I+ Q++S
Sbjct: 818 FDFANLEYNSNKYSIYILLIAIAMFISETLKNYYNNKIGEKVEKTMKRRLFENILYQEMS 877
Query: 75 WYD 77
++D
Sbjct: 878 FFD 880
Database: swissprot36
Posted date: Feb 26, 1999 3:43 PM
Number of letters in database: 26,840,295
Number of sequences in database: 74,019
Lambda K H
0.326 0.142 0.447
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11952436
Number of Sequences: 74019
Number of extensions: 468292
Number of successful extensions: 1323
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1243
Number of HSP's gapped (non-prelim): 83
length of query: 222
length of database: 26840295
effective HSP length: 45
effective length of query: 177
effective length of database: 23509440
effective search space: 4161170880
effective search space used: 4161170880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.6 bits)
S2: 63 (29.0 bits)
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Last modified: Sun, 23 May 1999,
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